Can you get high on MAOIs?
Rarely, an MAOI can cause dangerously high levels of serotonin, known as serotonin syndrome. It most often occurs when two medications that raise serotonin are combined.
Can I vape with antidepressants?
Fortunately, nicotine-replacement therapy does not interfere with antidepressant or antipsychotic medications.Nov 13, 2019
Is nicotine a MAOI?
Although nicotine causes increases in brain dopamine, it does not affect MAO levels, research has shown. Thus it appears that another component of tobacco smoke is inhibiting MAO.Jul 1, 1998
Do cigarettes have MAOI?
Because tobacco smoke contains monoamine oxidase inhibitors (MAOIs) and decreases MAO activity in smokers, we have combined MAOIs with nicotine to determine whether it is possible to obtain a locomotor response to nicotine in C57Bl6 mice.Dec 14, 2005
Can you vape while on escitalopram?
No interactions were found between Lexapro and nicotine.
Can you vape while on birth control?
Are there risks associated with vaping or using e-cigarettes while taking birth control? Just like regular cigarettes, most e-cigarettes contain nicotine, which is known to increase your blood pressure and heart rate. To be safe, it's best to avoid any products that contain nicotine while on hormonal birth control.Nov 29, 2021
Are MAOIs addictive?
Abuse of monoamine oxidase inhibitors is not common but there are a few cases of addiction in the literature. Most of these patients had an additional diagnosis, either history of past drug abuse or personality disorder and MAOI withdrawal symptoms have been reported.
Is nicotine a psychotropic?
Nicotine is a psychoactive substance that produces centrally mediated effects on mood as well as on heart, lungs, gastric motility, neurotransmitters, sympathetic and parasympathetic nervous systems. It acts as a biologic rein- forcer of the complex behavioral patterns of cigarette smoking.
Does tobacco have psychoactive properties?
Tobacco is a plant that contains nicotine, a psychoactive (mind altering) drug that speeds up activity in our central nervous system but has relaxing effects too.
Is cotinine psychoactive?
Preclinical findings reveal that cotinine crosses the blood brain barrier and interacts with both nAChRs and non-nAChRs in the nervous system, and produces neuropharmacological and behavioral effects. Clinical studies suggest that cotinine is psychoactive in humans.Oct 21, 2021
What are MAO inhibitors used for?
Monoamine oxidase inhibitors (MAOIs) are a separate class from other antidepressants, treating different forms of depression and other nervous system disorders such as panic disorder, social phobia, and depression with atypical features.Aug 6, 2021
Is nicotine a depressant?
Nicotine acts as both a stimulant and a depressant to the central nervous system. Nicotine first causes a release of the hormone epinephrine, which further stimulates the nervous system and is responsible for part of the "kick" from nicotine-the drug-induced feelings of pleasure and, over time, addiction.
Gautama Senior Member Verified Member ECF Veteran
I'm not a scientist. In fact, when I'm reading scientific journals or websites, I often need to have another tab open in order to translate what the hell they're saying. Even though it seems to have been known for years that cigarette smoke contains MAOI's, I just learned about it a few weeks ago. For some reason this topic intrigues me.
NICnurse Super Member Verified Member ECF Veteran
I remember reading about this a few years ago. Many here have hypothesized that there is an MAOI effect when smoking cigarettes. It also explains why some people have a difficult time mentally with quitting tobacco cigarettes completely.
dr g Moved On ECF Veteran
Depression caused by reduced MAOI effects is best treated with more LMAOs.
suspectK Vaping Master Verified Member ECF Veteran
ADD just means your brain knows there's something better you can be doing with yourself. The only thing real I've noticed with having 'ADD' is seeming to have a different reaction than others to depressive and stimulant substances.
suspectK Vaping Master Verified Member ECF Veteran
There's a lot of stuff in cigarettes that potentiate nicotine. Ammonia is added to nicotine in cigarette production. This turns nicotine into a freebase which gives it a better affinity for receptor bonding. Paired up with the several MAOI's with cigarette smoke and it is a rather different experience.
Gautama Senior Member Verified Member ECF Veteran
I guess my "attention issues" show because now that I look back at it, stating that I have ADD has absolutely nothing to do with what I was trying to say . Menthol is an MAOI!? I had no idea. I'd always been a menthol smoker and prefer it (or at least a strong mint) in all of my liquids.
suspectK Vaping Master Verified Member ECF Veteran
Since there are different MAOI's each one will have a different half life. The half life of the natural MAO A&B inhibitor, norharman?, is about 30 minutes, so about 2 hours there is practically 0-effectiveness of it.
I'm an Atheist who found spirituality through mushrooms and meditation. Told my sister that taking mushrooms was more spiritual for me than going to church. She got angry. But here's my question..
Respectfully. My question is, why do people view biblical spiritual experiences as something to be believed (talking animals, resurrections, etc.) But think that ACTUAL spiritual experiences are bad??? In other words, if I believe in the spiritual experiences of those in the Bible, then that's considered GOOD by my peers.
No more fear, no more anxiety, where did it go?
I used to microdose shrooms which made me really introspective and in touch with my feelings. Recently switched to LSD. I barely notice any effects on a supposedly 15ug volumetric dose. But changes have been coming.
