" " What Is Polyethylene Glycol 400 Used In Vape Pens

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what is polyethylene glycol 400 used in vape pens

by Prof. Rogelio Bednar Jr. Published 2 years ago Updated 1 year ago
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Commonly found in creams, shampoos, eye drops, vitamins and suppositories, PEG-400 is a pharmaceutical-grade product that can create formaldehyde at smoldering temperatures. About 10% of the oil in the Bloom Farms cartridges for their Highlighter pens consists of PEG-400.

PEGs have also been found in vape products (Traboulsi et al., 2020). PEG 400 is a low molecular weight grade of PEG that is widely used in cosmetics and pharmaceutical formulations as a solvent/lubricant due to its low oral and dermal toxicity.Jun 21, 2021

Full Answer

Do you offer polyethylene glycol 400?

We offer Polyethylene glycol 400, PEG 400 in many different grades and packaging sizes. For pricing and to see how you can save money on your PEG 400 please do not hesitate to request pricing today.

What is PEG 400 vape oil?

The boiling point of PEG 400 is higher than many MCT oils, making it a relatively safe chemical to be used in the vaping industry. Within the pharmaceutical industry, PEG 400 is used as a solvent, plasticizer, and a surfactant to lower the surface tension of water.

Should I use propylene glycol or polyethylene glycol in my portable vaporizer?

When purchasing oil cartridges for your portable vaporizer, check the ingredients to see if propylene glycol and/or polyethylene glycol 400 are listed. If so, you may want to avoid them and reach for an alternative product that utilizes terpenes or more health-conscious thinning agents.

Does polyethylene glycol 400 produce formaldehyde?

The results showed that polyethylene glycol 400 produced much higher acetaldehyde and formaldehyde byproducts than the other three agents. Heating of the thinning agent propylene glycol also produced significantly greater formaldehyde byproduct.

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Is polyethylene glycol used in vape juice?

Most e-cigarette liquids do not contain ethylene glycol and, where present, it is at levels that are not likely to contribute significantly to adverse health effects.

What is PEG 400 vape?

PEG 400 (or Polyethylene Glycol 400) is a clear, colorless, viscous liquid used in the cannabis industry. The PEG 400 is a pharmaceutical grade product with low toxicity and its chemical formula is H(OCH2CH2)nOH.

What is difference between PG and PEG 400?

PG and PEG have dissimilar chemical structures. PG is a small, single molecule with 3 carbons and 2 OH groups ( ie a double alcohol). PEG is a multi-unit polymer with a differing molecular weight and backbone.

What is propylene glycol in Vapes?

Propylene Glycol is the primary ingredient in the majority of e-liquids and e-cigarette cartridges on the marketplace today. Most e-liquid contains at least 80% and as much as 92% propylene glycol. This is the ingredient that produces the smoke-like vapor when the e-cigarette is exhaled.

Is peg 400 safe to consume?

It is toxic in very high doses, but the amounts used in the food industry are minimal and safe for human consumption. PEG 400 can be used as a sweetener, and as a carrier for flavor, including in vaping products as a carrier for flavor, with or without tobacco.

Is peg 400 a solvent?

Abstract. Polyethylene glycol 400 (PEG400) is a commonly used co-solvent. Recent studies suggested that it might affect the systemic exposure of oral drugs based on mechanisms besides increasing their solubility.

Is polyethylene glycol toxic to humans?

Ethylene glycol poisoning through ingestion can cause noncardiogenic pulmonary edema and ARDS. Ethylene glycol poisoning can cause dysrhythmias and heart failure. Ethylene glycol toxicity is characterized by an osmolal gap and metabolic acidosis with an elevated anion gap.

Is PEG 400 the same as PEG 8?

For example, PEG-8 is also known as Polyethylene Glycol 400, where 400 represents the average molecular weight of the compound.

What are side effects of propylene glycol?

Although PG is generally considered safe, when used in high doses or for prolonged periods, PG toxicity can occur. Reported adverse effects from PG include central nervous system (CNS) toxicity, hyperosmolarity, hemolysis, cardiac arrhythmia, seizures, agitation, and lactic acidosis.

Is it safe to vape propylene glycol?

Yes - it's used as a food additive in many, many products, so you probably already consume it on a daily basis. Is propylene glycol safe to vape? Yes, to be clear, it is considered extremely safe, non-toxic, and has no cancer-causing properties, unlike tobacco!

Is it OK to inhale propylene glycol?

Propylene glycol (PG) is generally recognized as safe by oral, dermal or inhalation routes and has been a common ingredient in all American made tobacco cigarettes for seven decades (AAPHP website).

Is glycol safe in vapes?

For a simple example, most vape liquid uses propylene glycol – a completely harmless chemical that also makes asthma inhalers work – to suspend and deliver the flavorings. However, cheap, mass-market vapes have been found to contain diethylene glycol – an industrial solvent which is definitely poisonous.

What is a peg 400?

What is PEG 400, Polyethylene Glycol 400. PEG 400 is an abbreviation of polyethylene glycol 400 , and is a colorless viscous liquid. It has many applications due to its low toxicity, and it is soluble in water, alcohols, glycerin, among other liquids.

What does 400 mean in chemistry?

What does “400” mean? The number 400 is a reference to the average molecular weight of the PEG. In the case of PEG 400, the molecular weight is 400 unified atomic mass units (or “daltons”), allowing the composure of the compound to be known. A weight of 400 daltons is equivalent to a chain of around 9 ether repetitions within the molecule.

How many ether repetitions are in a 400 dalton chain?

A weight of 400 daltons is equivalent to a chain of around 9 ether repetitions within the molecule. Longer chains weigh more, shorter chains weigh less, and the number given after the PEG designation reflects this. Differences in molecular weight affect the viscosity of PEG, leading to different weights being used in different products ...

Is peg 400 safe for vaping?

It is toxic in very high doses, but the amounts used in the food industry are minimal and safe for human consumption. PEG 400 can be used as a sweetener, and as a carrier for flavor, including in vaping products as a carrier for flavor, with or without tobacco.

Is polyethylene glycol used in antifreeze?

Is it used in antifreeze? No, polyethylene glycol is not used in antifreeze – ethylene glycol is, and has different properties to PEG 400. Ethylene glycol is not suitable for consumption. We offer Polyethylene glycol 400, PEG 400 in many different grades and packaging sizes.

Is PEG 400 the same as printer ink?

Consuming food with PEG 400 contained within it is not the same as consuming printer ink, in the same way that consuming a cake is not the same as eating an egg. While one of the ingredients is the same, the end product is vastly different.

Is peg 400 oil safe?

The boiling point of PEG 400 is higher than many MCT oils, making it a relatively safe chemical to be used in the vaping industry. Within the pharmaceutical industry, PEG 400 is used as a solvent, plasticizer, and a surfactant to lower the surface tension of water.

What is VG in vapes?

Vegetable Glycerin (VG) Other medium chain triglycerides (MCT) Going beyond the cannabis oil itself, it’s also a good idea to look at the cartridge and even the vape. Immediate red flags can be seen in the cartridge itself. It’s best to avoid plastic and low-grade wire.

What is a cutting agent in vape cartridges?

Cutting agents are used in vape cartridges to thin out concentrates so they work better with vaping devices and atomizers. By making the oil compliant with these devices, manufacturers introduce potentially unhealthy chemicals into the cannabis oil. The most common and criticized cutting agent is polyethylene glycol (PEG), ...

What are terpenes in cartridges?

Terpene additives are another common addition to cartridges to enhance the flavor profile of the product. In fact, they are sometimes seen as an alternative to PEG and PG and also used to thin out thicker cannabis oils. Terpenes can be derived from cannabis itself or from other natural plants, and are generally safe for consumers.

What is a C annabis cartridge?

C annabis vape pens and cartridges are some of the most popular products on dispensary shelves for their ease of use and ability to deliver potent hits on-the-go. These products are quickly becoming one of the fastest rising segments of the cannabis market, experiencing 400% growth in 2016 alone. To fill the demand for vaporizer cartridges, new ...

What to look for when you are left guessing what additives may be in a product?

To cut down on the guessing, you can look for certain red flags. First, it’s best to avoid potentially unsafe additives and chemicals. Some of the top additives to watch out for are:

Is vape cartridge 100% cannabis?

Doubling down, producers are starting to focus on selling products with 100% cannabis-sourced products. This has created a top-shelf criteria for vape cartridges, much like alcohol. For now though, there appears to be room for both inexpensive, potentially harmful cartridges and the higher- end, more thoroughly sourced products. With a fragmented market and varying levels of concern on the issue, there should be room for all companies for the foreseeable future. However, we’re hoping that quality products will begin to drive out the lower-end options as the market continues to progress.

Do you have to inspect vape pen?

Always inspect your vape pen to ensure it's made with quality components. Currently, California and other markets suffer from a lack of regulation. Oversights in regulations extend from pesticide use in cannabis cultivation to what is allowed inside a vape cartridge.

MonsterTruck Full Member

Sedansa decided to use PEG 400 (Polyethylene Glycol 400) instead of PG in the new catridges. This topic will allow us to share information on that new product replacing PG.

taz3cat Ultra Member ECF Veteran

Sedansa, must of found it was cheaper, I would not purchase any of their carts or juice.

dc2k08 Ultra Member ECF Veteran

I don't know what the difference is but it is worth looking into. I was told recently by a Chinese supplier that PG is 'not so good for health' and that they could, if requested, not put it in the carts I was ordering.

gep Moved On

From Wiki: "...PEG 400 is widely used in a variety of pharmaceutical formulations."

TropicalBob Vaping Master ECF Veteran

Good find, Rated PG. For more on those propylene glycol germicidal properties, see http://www.e-cigarette-forum.com/forum/health-safety-e-smoking/1734-germ-killing-vapor.html

ratedPG Full Member ECF Veteran

Thanks, TBob. That Time magazine article you linked to, got me started in my PG research. I've found some more articles about PG vapor, listed in the toxicology report sticky thread, if anyone's interested.

Kate Moved On

I'd love to read more of those kind of upbeat views. It does all seem like doom and gloom around here sometimes ... why can't we imagine positive scenarios - we just think like victims so much that nothing good seems possible.

Harmful agents to avoid in cannabis oil

When vaporized, cannabis oils are frequently mixed with thinning agents for better performance in a vaporizing device. However, when some thinning agents are heated, potentially harmful carbonyl compounds can be produced.

Thinning agent alternatives in vaporizer cartridges

Producers of vaporizer cartridges are making a mass exodus away from these thinning agents due to their health risks and the unpleasant taste they tend to carry. Instead, many are turning to terpenes as they help thin the oil while improving flavor.

Why use terpenes in oil?

Instead, many are turning to terpenes as they help thin the oil while improving flavor. Others are using different extraction methods such as CO2 extraction to achieve an oil thin enough to be consumed in a cartridge without the need for additive thinners.

Can you heat e-cigarettes?

However, there is no research regarding heating of thinning agents in vaporizing devices specifically designed for cannabis.

Is there a safety test for vape pen?

Furthermore, there has been a lack of adequate safety testing for the vape pen devices. Pre-packaged oil cartridges are not well labeled in some cases, and thinning agents are frequently developed in countries that have no regulatory controls.

Is vaping safer than smoking?

Since combustion does not occur, smoke is not created. People who vape cannabis perceive vaping to be safer and less harmful to their health than smoking.

What is the most common cutting agent in vape oil?

Most vape oils are comprised largely with ingredients other than the beneficial cannabis compounds, and are usually diluted with one or a mixture of cutting agents, the most common being: Polyethylene glycol (PEG) Propylene glycol (PG) Vegetable glycerin (VG) Coconut oil or MCT oil.

What are terpenes in vape oil?

Terpenes as Additives. In addition to natural and artificial flavorings, terpenes can be added for flavor and effect. The quality and source of the terpenes used in the vape oil goes a long way in determining if these compounds are beneficial, or harmful.

What is distilled oil?

A distilled oil is referred to as a distillate. In the distillation process, the plant material containing the valuable cannabinoids and flavonoids is first extracted using traditional means like CO2. Then, companies like Evolab utilize fractional distillation, allowing them to “boil off” the pure cannabinoid fraction from raw CO2 oil, thereby producing a clear, potent product that typically ranges between 85-95% total cannabinoids.

What are the side effects of inhaling PG?

The most common side effects of inhalation of a PG-containing product are dry mouth, sore throat, and increased thirst. However, it is important to note that there are currently no documented scientific studies on the safety of inhaling propylene glycol that has been heated or burned. Despite this alarming fact, ...

What is Evolab cannabis?

Evolab created the world’s first suite of cannabis specific pharmaceutical-grade extraction technologies. We produce exceptionally pure oils, without the use of any cutting agents. Our proprietary technology is designed to preserve the compounds of the …

Does coconut oil dry out a vape pen?

These oils tend to have a hard time getting wicked up into the atomizer, often resulting in a vape pen that is prone to running dry. Additionally, many users also report an unpleasant aftertaste in their mouths after using a product that has been cut with coconut oil or MCT oil.

Can you mix VG with other oils?

VG does not mix particularly well with other oil-based materials. For this reason, you will often see VG combined with one or more other cutting agents or additives. Vape oils laced with VG tend to create large, thick “smoke” cloud.

What are the additives in vape pens?

Common additives in cannabis oil vape pens, such as Propylene Glycol (PG) and polyethylene glycol (PEG), can result in exposure to harmful carcinogenic compounds when heated and inhaled. PEG, PG, and some pesticides degrade into stronger toxins at temperatures that vape pens can reach.

Is propylene glycol a thinning agent?

Jahan Marcu that exposed the potential hazards of heating and inhaling propylene glycol (PG), a widely used thinning agent in many cannabis oil products, including vape pen cartridges.

Is PG in a vaporizer?

Project CBD was the first cannabis industry watchdog to call attention to research showing that when PG is heated in an electronic vaporizer, it can decompose into formaldehyde, a potent carcinogen. They noted with concern that thinning agents such as PG are typically present in hemp -derived CBD oil extracts.

Is vaporizing cannabis better than smoking?

Vaporizing cannabis is supposed to be a healthier mode of administration than smoking cannabis. But much depends on the quality of the product. In theory, vaporization is supposed to heat the oil enough to release volatile terpenes and cannabinoid compounds (THC, CBD) into the air, but not enough to create smoke.

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What Is Peg 400?

  • PEG is short for polyethylene glycol, a liquid that is colorless as well as vicious. It can be dissolved in many other liquids such as water, along with alcohol and glycerin. It can also dissolve in acetone, benzene, and glycols. PEG 400 is just one form of PEG with its number specifying its average molecular weight. Different PEG forms have chemical structures that are in the form of …
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Benefits

  • What are the benefits of PEG 400? PEG 400 has various benefits which extend to many areas 1. It has less hazardous materials compared to smoke – smoke from nicotine has more than 7000 different chemicals, the majority of which are toxic. It’s not known exactly how many chemicals are produced by an electronic cigarette, but it’s believed it’s not as many. 2. Can be used in for v…
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What Is Vaping?

  • Vaping is a new style for nicotine and cannabis users to take their substance without smoking. To do this, you start with an e-liquid that is vaporized by an electronic cigarette (e-cigarette). Vaping has become widespread because the popularity of E-cigarette has shot up in the US, especially among the youth. It has overtaken other methods of consuming nicotine or tobacco products. I…
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Side Effects

  • PEG is generally a biologically inactive substance, so it is usually safe. However, it may have the following few side effects 1. It has been found to have toxic effects on rats 2. Likely to carry DEG contamination during its production process 3. Some people are allergic to it 4. It may potentially carry some harmful impurities such as ethylene oxide which is irritating to the skin
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Conclusion

  • PEG 400 is a liquid compound that is useful in many areas. In vaping, it remains the most popular e-liquid option for cannabis products. However, in e-cigarettes, it has fallen out of favor to be replaced by PG and VG. Today you will hardly get an e-cigarette that uses PEG 400. Beyond its use in vaping, PEG 400 has various applications that are che...
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